Skin-Resident Innate Lymphoid Cells – Cutaneous Innate Guardians and Regulators
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چکیده
منابع مشابه
Innate lymphoid cells and the skin
Innate lymphoid cells are an emerging family of effector cells that contribute to lymphoid organogenesis, metabolism, tissue remodelling and protection against infections. They maintain homeostatic immunity at barrier surfaces such as lung, skin and gut (Nature 464:1367-1371, 2010, Nat Rev Immunol 13: 145-149, 2013). Several human and mouse studies suggest a role for innate lymphoid cells in in...
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Purpose of review: The purpose of this article is to review recent advances in our understanding of innate lymphoid cell function and to speculate on how these cells may become activated and influence the immune response to allogeneic tissues and cells following transplantation. Recent findings: Innate lymphoid cells encompass several novel cell types whose wide ranging roles in the immune syst...
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Innate lymphoid cells (ILCs) are lymphoid cells that do not express rearranged receptors and have important effector and regulatory functions in innate immunity and tissue remodeling. ILCs are categorized into 3 groups based on their distinct patterns of cytokine production and the requirement of particular transcription factors for their development and function. Group 1 ILCs (ILC1s) produce i...
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ژورنال
عنوان ژورنال: Trends in Immunology
سال: 2020
ISSN: 1471-4906
DOI: 10.1016/j.it.2019.12.004